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1

Synthetic, Mechanistic and Biological Interrogation of Ginkgo biloba Chemical Space en route to (â)-Bilobalide

Demoret, Robert M., Baker, Meghan A., Ohtawa, Masaki, Chen, Shuming, Lam, Ching-Ching, Khom, Sophia, Roberto, Marisa, Forli, Stefano, Houk, K. N., Shenvi, Ryan A.

Journal:

Journal of the American Chemical Society

Year:

2020

File:

PDF, 24.21 MB

2020

2

Efficient Modulation of γ-Aminobutyric Acid Type A Receptors by Piperine Derivatives

Schöffmann, Angela, Wimmer, Laurin, Goldmann, Daria, Khom, Sophia, Hintersteiner, Juliane, Baburin, Igor, Schwarz, Thomas, Hintersteininger, Michael, Pakfeifer, Peter, Oufir, Mouhssin, Hamburger, Matt

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 6.18 MB

english, 2014

3

Modulation of GABA A Receptors by Valerian Extracts is Related to the Content of Valerenic Acid

Trauner, Gabriele, Khom, Sophia, Baburin, Igor, Benedek, Birgit, Hering, Steffen, Kopp, Brigitte

Journal:

Year:

2008

Language:

english

File:

PDF, 206 KB

english, 2008

4

Assessing the Impact of Industrial Policies on Economic Development in Nepal

Kharel, Khom Raj

Journal:

Economic Journal of Development Issues

Year:

2016

Language:

english

File:

PDF, 506 KB

english, 2016

5

Oxytocin blocks enhanced motivation for alcohol in alcohol dependence and blocks alcohol effects on GABAergic transmission in the central amygdala

Tunstall, Brendan J., Kirson, Dean, Zallar, Lia J., McConnell, Sam A., Vendruscolo, Janaina C. M., Ho, Chelsea P., Oleata, Christopher S., Khom, Sophia, Manning, Maurice, Lee, Mary R., Leggio, Lorenzo

Journal:

Year:

2019

Language:

english

File:

PDF, 2.18 MB

english, 2019

6

MODIS-Based Investigation of Flood Areas in Southern Cambodia from 2002–2013

Vichet, Nguon, Kawamura, Kensuke, Trong, Dung Phan, On, Nguyen Van, Gong, Zhe, Lim, Jihyun, Khom, Sok, Bunly, Chhun

Journal:

Year:

2019

Language:

english

File:

PDF, 7.13 MB

english, 2019

7

Benzodiazepines modulate GABAAreceptors by reducing a gamma-subunit-mediated inhibition of GABA sensitivity

Igor Baburin, Sophia Khom, Eugen Timin, Annette Hohaus, Werner Sieghart, Steffen Hering

Journal:

BMC Pharmacology

Year:

2009

Language:

english

File:

PDF, 113 KB

english, 2009

8

Mixed finite-element method for the improved statement of the problem of interlayer contact. Part 1. Principal relations and the general procedure of construction of computational schemes in the {m, n}-approximation

M. V. Marchuk, M. M. Khom'yak

Journal:

Strength of Materials

Year:

2000

Language:

english

File:

PDF, 518 KB

english, 2000

9

Mixed finite-element method for the improved statement of the problem of interlayer contact. Part 2. Numerical analysis of contact bending stresses in layered plates

M. V. Marchuk, M. M. Khom'yak

Journal:

Strength of Materials

Year:

2000

Language:

english

File:

PDF, 409 KB

english, 2000

10

Valerenic acid derivatives as novel subunit-selective GABAA receptor ligands –in vitro and in vivo characterization

S Khom, B Strommer, J Ramharter, T Schwarz, C Schwarzer, T Erker, GF Ecker, J Mulzer, S Hering

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 1.38 MB

english, 2010

11

Estimating the efficiency of benzodiazepines on GABAA receptors comprising γ1 or γ2 subunits

I Baburin, S Khom, E Timin, A Hohaus, W Sieghart, S Hering

Journal:

British Journal of Pharmacology

Year:

2008

Language:

english

File:

PDF, 243 KB

english, 2008

12

A mechanism of decomposition of vaporized formic acid over metallic palladium

A.A. Khom'yenko, L.O. Apel'ba'oom, M.I. T'yomkeen

Journal:

Journal of Catalysis

Year:

1967

Language:

english

File:

PDF, 190 KB

english, 1967

13

Diabetes and cardiovascular risk factor controls in Thai type 2 diabetes with no history of cardiovascular complications; situation and compliance to diabetes management guideline in Thailand

Patcharaporn Sudchada, Chayada Khom-ar-wut, Anuchit Eaimsongchram, Saksipong Katemut, Piwadee Kunmaturos, Rawisut Deoisares

Journal:

Journal of Diabetes and its Complications

Year:

2012

Language:

english

File:

PDF, 190 KB

english, 2012

14

Valerenic acid potentiates and inhibits GABAA receptors: Molecular mechanism and subunit specificity

S. Khom, I. Baburin, E. Timin, A. Hohaus, G. Trauner, B. Kopp, S. Hering

Journal:

Neuropharmacology

Year:

2007

Language:

english

File:

PDF, 910 KB

english, 2007

15

Dehydration of methanol to dimethyl ether over nanocrystalline Al2O3 with mixed γ- and χ-crystalline phases

Jutharat Khom-in, Piyasan Praserthdam, Joongjai Panpranot, Okorn Mekasuwandumrong

Journal:

Catalysis Communications

Year:

2008

Language:

english

File:

PDF, 225 KB

english, 2008

16

Identification and Characterization of GABA A Receptor Modulatory Diterpenes from Biota orientalis That Decrease Locomotor Activity in Mice

Zaugg, Janine, Khom, Sophia, Eigenmann, Daniela, Baburin, Igor, Hamburger, Matthias, Hering, Steffen

Journal:

Journal of Natural Products

Year:

2011

Language:

english

File:

PDF, 1.49 MB

english, 2011

17

GABAA receptor modulation by piperine and a non-TRPV1 activating derivative

Khom, Sophia, Strommer, Barbara, Schöffmann, Angela, Hintersteiner, Juliane, Baburin, Igor, Erker, Thomas, Schwarz, Thomas, Schwarzer, Christoph, Zaugg, Janine, Hamburger, Matthias, Hering, Steffen

Journal:

Biochemical Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.76 MB

english, 2013

18

Esters of valerenic acid as potential prodrugs

Hintersteiner, Juliane, Haider, Maximilian, Luger, Denise, Schwarzer, Christoph, Reznicek, Gottfried, Jäger, Walter, Khom, Sophia, Mihovilovic, Marko D., Hering, Steffen

Journal:

European Journal of Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.12 MB

english, 2014

19

Commentary from Westminster

Hintersteiner, Juliane, Haider, Maximilian, Luger, Denise, Schwarzer, Christoph, Reznicek, Gottfried, Jäger, Walter, Khom, Sophia, Mihovilovic, Marko D., Hering, Steffen

Journal:

Year:

1978

Language:

english

File:

PDF, 451 KB

english, 1978

20

Design and evaluation of a lyophilized liposomal gel of an antiviral drug for intravaginal delivery

Manne, Navya, Yadav, Hemant K. S., Kumar, S. Hemanth, Khom, Tashi Chojjom, Kumar, N. Sankeerth

Journal:

Journal of Applied Polymer Science

Year:

2014

Language:

english

File:

PDF, 546 KB

english, 2014

21

Bioactivity-Guided Isolation of GABA A Receptor Modulating Constituents from the Rhizomes of Actaea racemosa

Cicek, Serhat S., Khom, Sophia, Taferner, Barbara, Hering, Steffen, Stuppner, Hermann

Journal:

Journal of Natural Products

Year:

2010

Language:

english

File:

PDF, 216 KB

english, 2010

22

A Cycloartane Glycoside Derived from Actaea racemosa L. Modulates GABAA Receptors and Induces Pronounced Sedation in Mice

Strommer, B., Khom, S., Kastenberger, I., Cicek, S. S., Stuppner, H., Schwarzer, C., Hering, S.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2014

Language:

english

File:

PDF, 707 KB

english, 2014

23

Synthesis and Biological Characterization of Novel Charge-Deficient Spermine Analogues

Weisell, Janne, Hyvönen, Mervi T., Häkkinen, Merja R., Grigorenko, Nikolay A., Pietilä, Marko, Lampinen, Anita, Kochetkov, Sergey N., Alhonen, Leena, Vepsäläinen, Jouko, Keinänen, Tuomo A., Khom

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.18 MB

english, 2010

24

Developing piperine towards TRPV1 and GABA A receptor ligands – synthesis of piperine analogs via Heck-coupling of conjugated dienes

Wimmer, Laurin, Schönbauer, David, Pakfeifer, Peter, Schöffmann, Angela, Khom, Sophia, Hering, Steffen, Mihovilovic, Marko D.

Journal:

Organic & Biomolecular Chemistry

Year:

2015

Language:

english

File:

PDF, 385 KB

english, 2015

25

Pharmacological Properties of GABAA Receptors Containing 1 Subunits

Journal:

Molecular Pharmacology

Year:

2005

Language:

english

File:

PDF, 504 KB

english, 2005

26

GABA A Receptor Modulators from the Chinese Herbal Drug Junci Medulla - The Pith of Juncus effusus

Singhuber, Judith, Baburin, Igor, Khom, Sophia, Zehl, Martin, Urban, Ernst, Hering, Steffen, Kopp, Brigitte

Journal:

Year:

2012

Language:

english

File:

PDF, 117 KB

english, 2012

27

Development of Mucoadhesive Nanoparticulate System of Ebastine for Nasal Drug Delivery

Khom, TC, Yadav, HKS, Raizaday, A, Manne, N, Kumar, HS, Kumar, SN

Journal:

Tropical Journal of Pharmaceutical Research

Year:

2014

Language:

english

File:

PDF, 520 KB

english, 2014

28

HPLC-Based Activity Profiling Approach for the Discovery of GABA A Receptor Ligands using an Automated Two Microelectrode Voltage Clamp Assay on Xenopus Oocytes

Kim, Hyun, Baburin, Igor, Khom, Sophia, Hering, Steffen, Hamburger, Matthias

Journal:

Year:

2008

Language:

english

File:

PDF, 292 KB

english, 2008

29

Analysis of -subunit-dependent GABAA receptor modulation and behavioral effects of valerenic acid derivatives

Khom, S., Hintersteiner, J., Luger, D., Haider, M., Pototschnig, G., Mihovilovic, M. D., Schwarzer, C., Hering, S.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2016

Language:

english

File:

PDF, 1.02 MB

english, 2016

30

Identification of the putative binding pocket of valerenic acid on GABA A receptors using docking studies and site-directed mutagenesis

Luger, D, Poli, G, Wieder, M, Stadler, M, Ke, S, Ernst, M, Hohaus, A, Linder, T, Seidel, T, Langer, T, Khom, S, Hering, S

Journal:

British Journal of Pharmacology

Year:

2015

Language:

english

File:

PDF, 2.83 MB

english, 2015

31

Chronic ethanol-induced immune responses in the mouse central amygdala: Focus on glia and IL-1 system

Bajo, Michal, Steinman, Michael Q., Varodayan, Florence P., Khom, Sophia, Patel, Reesha R., Hedges, David M., Herman, Melissa A., Montgomery, Sarah E., Nadav, Tali, Steiner, Noah, Mandyam, Chitra D.,

Journal:

Year:

2017

Language:

english

File:

PDF, 39 KB

english, 2017

32

Alcohol dependence alters substance P/neurokinin 1 receptor signaling in the central nucleus of the amygdala

Khom, S., Rice, K.C., Roberto, M.

Journal:

Year:

2017

Language:

english

File:

PDF, 41 KB

english, 2017

33

CRF modulates glutamate transmission in the central amygdala of naïve and ethanol-dependent rats

Varodayan, Florence P., Correia, Diego, Kirson, Dean, Khom, Sophia, Oleata, Christopher S., Luu, George, Schweitzer, Paul, Roberto, Marisa

Journal:

Neuropharmacology

Year:

2017

Language:

english

File:

PDF, 1.57 MB

english, 2017

34

Role of TLR4 in the Modulation of Central Amygdala GABA Transmission by CRF Following Restraint Stress

Varodayan, F P, Khom, S, Patel, R R, Steinman, M Q, Hedges, D M, Oleata, C S, Homanics, G E, Roberto, M, Bajo, M

Journal:

Alcohol and Alcoholism

Year:

2018

Language:

english

File:

PDF, 571 KB

english, 2018

35

Design, synthesis and pharmacological evaluation of novel β2/3 subunit-selective γ-Aminobutyric Acid Type A (GABAA) receptor modulators

Stadler, Marco, Monticelli, Serena, Seidel, Thomas, Luger, Denise, Salzer, Isabella, Boehm, Stefan, Holzer, Wolfgang, Schwarzer, Christoph, Urban, Ernst, Khom, Sophia, Langer, Thierry, Pace, Vittorio,

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.38 MB

english, 2018

36

IL-1β expression is increased and regulates GABA transmission following chronic ethanol in mouse central amygdala

Patel, Reesha R., Khom, Sophia, Steinman, Michael Q., Varodayan, Florence P., Kiosses, William B., Hedges, David M., Vlkolinsky, Roman, Nadav, Tali, Polis, Ilham, Bajo, Michal, Roberts, Amanda J., Rob

Journal:

Brain, Behavior, and Immunity

Year:

2018

Language:

english

File:

PDF, 2.17 MB

english, 2018

37

MODIS-Based Investigation of Flood Areas in Southern Cambodia from 2002–2013

Vichet, Nguon, Kawamura, Kensuke, Trong, Dung Phan, On, Nguyen Van, Gong, Zhe, Lim, Jihyun, Khom, Sok, Bunly, Chhun

Journal:

Year:

2019

File:

PDF, 7.13 MB

2019

38

Cessation of fluoxetine treatment increases alcohol seeking during relapse and dysregulates endocannabinoid and glutamatergic signaling in the central amygdala

Suárez, Juan, Khom, Sophia, Alén, Francisco, Natividad, Luis A., Varodayan, Florence P., Patel, Reesha R., Kirson, Dean, Arco, Rocío, Ballesta, Antonio, Bajo, Michal, Rubio, Leticia, Martin‐Fardon, Ré

Journal:

Addiction Biology

Year:

2019

File:

PDF, 991 KB

2019

39

Increased IL-6 expression in astrocytes is associated with emotionality, alterations in central amygdala GABAergic transmission, and excitability during alcohol withdrawal

Roberts, Amanda J., Khom, Sophia, Bajo, Michal, Vlkolinsky, Roman, Polis, Ilham, Cates-Gatto, Chelsea, Roberto, Marisa, Gruol, Donna L.

Journal:

Brain, Behavior, and Immunity

Year:

2019

Language:

english

File:

PDF, 2.40 MB

english, 2019

40

The Role of the Central Amygdala in Alcohol Dependence

Roberto, Marisa, Kirson, Dean, Khom, Sophia

Journal:

Cold Spring Harbor Perspectives in Medicine

Year:

2020

File:

PDF, 875 KB

2020

41

Microglia control escalation of drinking in alcohol dependent mice: Genomic and synaptic drivers

Warden, Anna S., Wolfe, Sarah A., Khom, Sophia, Varodayan, Florence P., Patel, Reesha R., Steinman, Michael Q., Bajo, Michal, Montgomery, Sarah, Vlkolinsky, Roman, Nadav, Tali, Polis, Ilham, Roberts,

Journal:

Biological Psychiatry

Year:

2020

File:

PDF, 18.23 MB

2020

42

Alcohol dependence and withdrawal impair serotonergic regulation of GABA transmission in the rat central nucleus of the amygdala

Khom, Sophia, Wolfe, Sarah A., Patel, Reesha R., Kirson, Dean, Hedges, David M., Varodayan, Florence P., Bajo, Michal, Roberto, Marisa

Journal:

Journal of Neuroscience

Year:

2020

File:

PDF, 2.63 MB

2020

43

Importance of sex and trauma context on circulating cytokines and amygdalar GABAergic signaling in a comorbid model of posttraumatic stress and alcohol use disorders

Steinman, Michael Q., Kirson, Dean, Wolfe, Sarah A., Khom, Sophia, DâAmbrosio, Shannon R., Spierling Bagsic, Samantha R., Bajo, Michal, VlkolinskÃ½, Roman, Hoang, Noah K., Singhal, Anshita, Sureshch

Journal:

Molecular Psychiatry

Year:

2020

File:

PDF, 1.11 MB

2020

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